Pharmacological approach to induced anaphylactic shock (AS) in rats

Anaphylactic shock induced by diclofenac.

Diclofenac is a non-steroidal anti-inflammatory agent used in degenerative joint disease, rheumatoid arthritis, and allied conditions.' Its commonest unwanted effects include gastrointestinal disorders, rashes, peripheral oedema, and abnormalities of serum transaminase activity. More rarely, melaena and haematemesis, myoclonic encephalopathy, and myoclonus of the lower limbs may occur.2 3 We re...

Anaphylactic shock to raspberry.

A Case of Pranlukast-Induced Anaphylactic Shock.

Leukotriene receptor antagonists, which are generally considered safe with a few adverse drug reactions, are increasingly used in the treatment of various allergic diseases, including asthma and allergic rhinitis. Although a few anaphylactic reactions to montelukast have been reported worldwide, there is still a lack of reports about severe adverse drug reactions associated with pranlukast. Her...

Anaphylactic Shock

Anaphylactic shock is an unexpected, sudden and sometimes deadly event that attacks the patient in 75% of the cases without pre-existent history of allergy. In general, drugs, hymenopteric poisons and nutrients (according to the recent concept) are responsible. Beside the classical IgE-mediated anaphylactic shock there exists another anaphylactic shock, identical in its clinical picture and tre...

Clindamycin-induced anaphylactic shock during general anesthesia.

Clindamycin-related anaphylactic reaction is rarely reported. We report a male patient with buccal cancer who was undergoing radical neck dissection when life-threatening anaphylactic shock developed soon after intravenous infusion of clindamycin. Immediate cardiopulmonary resuscitation was performed, and the patient recovered uneventfully. Perioperative anaphylactic shock is a serious problem ...